Hubei Biocause Phamaceutical Co., Ltd.
#122Yangwan Road,Jingmen, Hubei, China
Tel.:++86 (0)27 65651730 / 85628285
Fax.:++86 (0)27 65652329
Email:export@biocause.com,export@biocause.net
Contract Research
Located in Wuhan China, our R&D center is awarded as Innovation Company of Hubei
province, and appointed by local government for industrial technology transferring site
and cooperation with domestic Post-doctors. In addition, we have long collaborations
with Institute of Materia Medica (CAMS), Shanghai Institute of Organic Chemistry(CAS) ,
Wuhan University, Tongji Medical College of Huazhong University of Science & Technology,
and etc.
■Consistently synthesize chemical entities as per customer’s requirements
■Develop patent non-infringing processes for patented generics
■Troubleshoot chemistry issues through in-house technical expertise
■Develop analytical methods and quick turnaround of analytical results
■Identify and prepare impurities/reference standards
■Constantly manage customer project through PM team and PM program
Process Capabilities
Organic Reactions
Chiral Synthesis Heterocyclization
Metallic Organic Reaction Grignard reaction
Nucleophilic substitution reaction Esterification
Suzuki reaction Elimination reaction
Alkylation Glycochemistry
Preparative HPLC
Rectification Resin Purification
Friedel-Crafts Reaction Halogenation
Cyanation Sulfonation
Condensation Nitration
Hydrolyzation Hydrogenation
Diazotisation Oxidation
Reduction Pericyclic Reaction
Non-water & non-oxygen reaction
Various Protection and Deprotection Techniques
To develop patent non-infringing processes, we would
■Try to repeat active patents, remove the disturbing information
■Evaluate key points of active patents, make mass of parallel tests to find alternative proposals
■Evaluate alternative proposals, choose the most suitable one
■Complete new process
■Apply process patent worldwide for the new process
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